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The Drugs of Abuse: An Overview

Central Nervous System Depressants

This category includes the most widely abused drug, alcohol. In addition, the category consists of barbiturates, non-barbiturates that have barbiturate-like effects, anti-anxiety tranquilizers, anti-psychotic tranquilizers, certain anti-depressants, and certain pharmaceutical combinations that contain more than one type of CNS Depressant. The benzodiazepines, chloral hydrate, GHB, methaqualone (Mandrax), lithium, phenobarbital, the sedating antihistamines, and many other substances are included in this category. Commonly referred to as "downers," and also as sedative-hypnotics, the effects of these drugs at intoxicating doses mirror the effects of alcohol.

Importantly, however, they are not detected by an alcohol breath test, and do not produce an odor of an alcoholic beverage. Unlike the case with alcohol, there are generally no consistent correlations between the levels of these drugs ingested and the degree of intoxication. These drugs produce relaxation, drowsiness, impaired balance and coordination, slurred speech, a lowering of inhibitions, and increased risk taking. They also produce horizontal gaze nystagmus, do not generally affect pupil size, and typically depress the vital signs. The non-alcohol CNS Depressants are extremely dangerous when taken with alcohol. Pharmaceutical preparations of these drugs usually contain warnings advising the user not to drink alcohol at the same time, and to be aware that they may impair driving.

Central Nervous System Stimulants

This category includes the ubiquitous cocaine in all its various forms, amphetamine, methamphetamine, ephedrine, Ritalin, certain diet pills, and other related substances. Commonly known as the "uppers," the effects of these drugs mimic the body's "fight or flight" response, the autonomic nervous system's response to perceived danger. Their effects include dilated pupils, elevated vital signs, hyper-alertness, rapid and agitated body movements, extreme weight loss accompanied by deteriorating health and hygiene, and a diminished ability to "filter" environmental stimuli, such as noises and movement. CNS Stimulants do not produce horizontal gaze nystagmus. The user may overreact to seemingly minor events, and may view minor inconveniences as

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elaborate plots. As the effects wear off, the user may physiologically "crash," and may appear nearly the opposite of when he or she was under the influence of the drug. The user may then sleep for long periods, may wake voraciously hungry, and may be extremely dysphoric.

Hallucinogens

Hallucinogens are used for their distorted sensory perceptions known as hallucinations. In many respects, they are closely related to the CNS Stimulants, as is evidenced by the fact that they also cause dilated pupils and elevated vital signs, and do not produce horizontal gaze nystagmus. The user may experience a mixing of the senses, called synesthesia, in which the user may "hear" visual stimuli, such as colors, and may "see" sounds, such as music. LSD, psilocybin, mescaline, peyote, bufotenine, morning glory seeds, jimson weed, nutmeg and the psychedelic amphetamines are some of the drugs in this category. The psychedelic amphetamines include MDMA, or methylenedioxy methamphetamine, which is known in the vernacular as "Ecstasy," and many other related preparations. Very popular in the 1960s, these drugs have experienced a resurgence of use in the 1990s.

Phencyclidine (PCP)

This drug is usually known as PCP, which represents its longer chemical name of phenylcyclohexyl piperidine. It is also commonly called phencyclidine. Although frequently classified as a hallucinogen, and sometimes as a depressant, a stimulant, or an analgesic, PCP is appropriately termed a dissociative anesthetic. The drug ketamine, which has uses in veterinary medicine, in pediatric surgery, and in other areas, is included in this category, as are chemical analogs of PCP.

The typical effects of PCP are elevated vital signs, accompanied by both horizontal and vertical gaze nystagmus. In addition, rigid skeletal muscles, a blank stare, an absence of pain, hallucinations, and many other effects may be evident. PCP users may become suddenly violent, and pose an extreme danger to police officers. Many non-lethal control devices, such as "taser" dart guns, have been developed in order to subdue the PCP user.

Narcotic Analgesics

This final category includes the opiates, such as morphine, codeine, percodan, heroin, meperidine, methadone, fentanyl, and numerous others. These drugs relieve pain, but also produce sedation. The specific effects include constricted pupils, depressed vital signs, slow and deliberate movements, and forgetfulness. These drugs do not produce horizontal gaze nystagmus. Although these drugs are frequently injected, more users, because of concern over the spread of infectious disease through the sharing of hypodermic needles, are insufflating (intranasal administration) and inhaling drugs such as heroin. These drugs are known for their physically addictive qualities, as well as for the extremely unpleasant, though not life-threatening, withdrawal syndrome.

Inhalants

The drugs in this category are usually inhaled. Three sub-categories comprise the inhalants: volatile solvents, aerosols, and anesthetic gases. The typical user of these drugs is young, and as a result, does not have ready access to more preferred drugs. Included are solvents, such as paint thinner, gasoline, toluene, turpentine, and paint. Nitrous oxide ("laughing gas"), freon, ether, and many other substances are also included. Common indicators of the use of these drugs are the presence of chemical odors on the user, and residue of the substance on the user's face, clothing, and hands. Intoxicated individuals may look and act similar to one under the influence of alcohol. They may display impaired gait, slurred speech, bloodshot eyes, and a blank stare. Since these substances displace oxygen, the heart generally will accelerate, resulting in an increased pulse rate. Depending on the specific substance, blood pressure can be elevated or depressed. 29 As with the CNS Depressants, these drugs generally produce horizontal gaze nystagmus, but do not usually affect pupil size.

Cannabis

This category, which includes marijuana, hash, hash oil, and the synthetic drug dronabinol, is the most widely abused illicit drug. Although it has a popular reputation as a relatively benign drug, it is extremely impairing, affecting judgment, depth perception, ability to maintain attention, as well as having effects on the cardiovascular system. Cannabis causes blood shot eyes, accelerated heart rate (tachycardia), muscle tremors, forgetfulness, and many other effects. Unlike the first three categories (CNS Depressants, Inhalants, and PCP), this category does not produce horizontal gaze nystagmus. Users of cannabis frequently use alcohol, as well as other drugs, at the same time.


This information is courtesy of http://www.azdps.gov/

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DISCLAIMER:   The foregoing is not to be construed as legal advice to or for any specific individual. Always seek the advice of counsel for specific legal problems.

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